This species differs from its congeners by having a concave dorsal head profile (vs. convex or straight); frontal bones broadly sutured to each other anterior to small, circular remnant foramen of anterior cranial fontanelle that is anteriorly adjacent to epiphyseal bar (vs. frontals separated by anterior fontanelle widely open from mesethmoid to epiphyseal bar). It differs from all epigean Rhamdia by the following troglomorphic characters: eyes absent, complete depigmentation, widened cutaneous pores of the cephalic laterosensory system, preoperculomandibular sensory canal forming wide fossae in the dentary and preopercle (vs. narrow pores and canals). Further, this species can be distinguished from other Rhamdia species by the following set of characters: pectoral fins with a spine and ten branched rays (vs. modally eight or nine soft rays in other species); both lobes of the caudal fin pointed (vs. at least one lobe rounded); caudal skeleton with three hypural plates, PH; 1 + 2; 3 + 4 + 5 (vs. Modally four PH; 1 + 2; 3 + 4; 5 in the other species, except R. laukidi and R. jequitinhonha) (Ref. 80467).